Fine‐needle aspiration cytology of soft tissue lesions: Diagnostic challenges

摘要: Clinical and radiographic data provide important information in the evaluation of soft tissue lesions/neoplasms. Morphologic cytologic examination is considered to be a necessary part diagnostic work-up. The standard procedure for obtaining tumor morphologic has been incisional (open) or core needle biopsy. An increasing use minimally invasive procedures resulted better acceptance fine-needle aspiration cytology (FNAC) diagnosis lesions. This article discusses challenges FNAC lesions based on experience at multidisciplinary referral sarcoma center. Obtaining sufficient specimens from deeply seated small necrotic/cystic technically potential pitfall misdiagnosis cells reactive zones surrounding as well correct spindle cell lesions, rare neoplasms, "new entities" lacking reproducible cytological criteria are other tissues. successful requires application strict, morphological context clinical findings ancillary techniques. minimal intervention various settings relative advantages disadvantages must understood. facilitated when limited specialized orthopedic-oncologic centers with well-integrated team therapy