作者: S. Eldabe , A. Lloyd , L. Verdian , M. Meguro , G. Maclaine
DOI: 10.1007/S10198-009-0178-X
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摘要: There is an absence of data on public preferences for health states (HSs) associated with severe chronic pain. The aim this study was to develop accurate HS descriptions pain requiring intrathecal (IT) therapy and derive utility weights that describe the health-related quality life (HRQL) impact malignant (MP) non-malignant (NMP) aetiologies. Eight visual analogue scale index (VAS-PI) HSs were defined using ranges 0–40, 41–60, 61–80 81–100 applied both MP NMP. Additionally, eight representing common adverse events IT identified. content description ascertained by interviews five United Kingdom clinical experts. In total, 16 compiled. These questionnaires administered 102 members public, utilising a time trade off (TTO) approach estimate utilities HSs. Participants generally well matched general in England Wales, some differences mean age, race education. A substantial decline observed more VAS-PI values. TTO values also decreased from mild able differentiate between side effects. shows clear decrement moving different severity levels