摘要: The past decade has seen significant advances in the treatment of childhood malignancies accompanied by appreciable improvement survival rates. Treatment programmes have been largely formulated to meet specific characteristics individual tumours, as well being based on extent disease presented at diagnosis. In selecting most appropriate protocol, accurate histological categorization resected or biopsied tumour is thus paramount importance. paediatric age range which so many tumours lack differentiation present as, mimic, other small cell routine methods are often insufficient resolve problematic histology. A wide special techniques now hand assist pathologist with this problem and review an attempt partly rationalize application available methodology. Of considerable importance also a knowledge behavioural group their prototypic histology, morphological variability.