Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids

作者: Annekatrien Depla , Egbert F. Smit , Koen J. Hartemink , Rosa de Groot , Monika C. Wolkers

DOI: 10.1016/J.CELL.2018.07.009

关键词:

摘要: … We demonstrate that co-cultures of autologous tumor organoids and peripheral blood lymphocytes can be used to enrich tumor-reactive T cells from peripheral blood of patients with …

参考文章(44)
Jan Willem F Dierssen, Noel FCC de Miranda, Soldano Ferrone, Marjo van Puijenbroek, Cees J Cornelisse, Gert Jan Fleuren, Tom van Wezel, Hans Morreau, HNPCC versus sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression BMC Cancer. ,vol. 7, pp. 33- 33 ,(2007) , 10.1186/1471-2407-7-33
Marc van de Wetering, Hayley E. Francies, Joshua M. Francis, Gergana Bounova, Francesco Iorio, Apollo Pronk, Winan van Houdt, Joost van Gorp, Amaro Taylor-Weiner, Lennart Kester, Anne McLaren-Douglas, Joyce Blokker, Sridevi Jaksani, Sina Bartfeld, Richard Volckman, Peter van Sluis, Vivian S.W. Li, Sara Seepo, Chandra Sekhar Pedamallu, Kristian Cibulskis, Scott L. Carter, Aaron McKenna, Michael S. Lawrence, Lee Lichtenstein, Chip Stewart, Jan Koster, Rogier Versteeg, Alexander van Oudenaarden, Julio Saez-Rodriguez, Robert G.J. Vries, Gad Getz, Lodewyk Wessels, Michael R. Stratton, Ultan McDermott, Matthew Meyerson, Mathew J. Garnett, Hans Clevers, Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients Cell. ,vol. 161, pp. 933- 945 ,(2015) , 10.1016/J.CELL.2015.03.053
Feriyl Bhaijee, Thomas Huebner, Ralph H. Hruban, Laura D. Wood, Nathan Cuka, Drew M. Pardoll, Nickolas Papadopoulos, Kenneth W. Kinzler, Shibin Zhou, Toby C. Cornish, Janis M. Taube, Robert A. Anders, James R. Eshleman, Bert Vogelstein, Luis A. Diaz, Dung T. Le, Jennifer N. Uram, Hao Wang, Bjarne R. Bartlett, Holly Kemberling, Aleksandra D. Eyring, Andrew D. Skora, Brandon S. Luber, Nilofer S. Azad, Dan Laheru, Barbara Biedrzycki, Ross C. Donehower, Atif Zaheer, George A. Fisher, Todd S. Crocenzi, James J. Lee, Steven M. Duffy, Richard M. Goldberg, Albert de la Chapelle, Minori Koshiji, PD-1 Blockade in Tumors with Mismatch-Repair Deficiency The New England Journal of Medicine. ,vol. 372, pp. 2509- 2520 ,(2015) , 10.1056/NEJMOA1500596
Cyrille J. Cohen, Jared J. Gartner, Miryam Horovitz-Fried, Katerina Shamalov, Kasia Trebska-McGowan, Valery V. Bliskovsky, Maria R. Parkhurst, Chen Ankri, Todd. D. Prickett, Jessica S. Crystal, Yong F. Li, Mona El-Gamil, Steven A. Rosenberg, Paul F. Robbins, Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes Journal of Clinical Investigation. ,vol. 125, pp. 3981- 3991 ,(2015) , 10.1172/JCI82416
Edward B Garon, Naiyer A Rizvi, Rina Hui, Natasha Leighl, Ani S Balmanoukian, Joseph Paul Eder, Amita Patnaik, Charu Aggarwal, Matthew Gubens, Leora Horn, Enric Carcereny, Myung-Ju Ahn, Enriqueta Felip, Jong-Seok Lee, Matthew D Hellmann, Omid Hamid, Jonathan W Goldman, Jean-Charles Soria, Marisa Dolled-Filhart, Ruth Z Rutledge, Jin Zhang, Jared K Lunceford, Reshma Rangwala, Gregory M Lubiniecki, Charlotte Roach, Kenneth Emancipator, Leena Gandhi, None, Pembrolizumab for the treatment of non-small cell lung cancer The New England Journal of Medicine. ,vol. 372, pp. 2018- 2028 ,(2015) , 10.1056/NEJMOA1501824
Chao Zheng, Yi-hua Sun, Xiao-lei Ye, Hai-quan Chen, Hong-bin Ji, Establishment and characterization of primary lung cancer cell lines from Chinese population. Acta Pharmacologica Sinica. ,vol. 32, pp. 385- 392 ,(2011) , 10.1038/APS.2010.214
Steven A. Rosenberg, Nicholas P. Restifo, Adoptive cell transfer as personalized immunotherapy for human cancer. Science. ,vol. 348, pp. 62- 68 ,(2015) , 10.1126/SCIENCE.AAA4967
Shuji Ogino, Katsuhiko Nosho, Natsumi Irahara, Jeffrey A. Meyerhardt, Yoshifumi Baba, Kaori Shima, Jonathan N. Glickman, Cristina R. Ferrone, Mari Mino-Kenudson, Noriko Tanaka, Glenn Dranoff, Edward L. Giovannucci, Charles S. Fuchs, Lymphocytic Reaction to Colorectal Cancer Is Associated with Longer Survival, Independent of Lymph Node Count, Microsatellite Instability, and CpG Island Methylator Phenotype Clinical Cancer Research. ,vol. 15, pp. 6412- 6420 ,(2009) , 10.1158/1078-0432.CCR-09-1438
Ton N. Schumacher, Robert D. Schreiber, Neoantigens in cancer immunotherapy Science. ,vol. 348, pp. 69- 74 ,(2015) , 10.1126/SCIENCE.AAA4971
May M. Y. Liang-Chu, Mamie Yu, Peter M. Haverty, Julie Koeman, Janet Ziegle, Marie Lee, Richard Bourgon, Richard M. Neve, Human Biosample Authentication Using the High-Throughput, Cost-Effective SNPtraceTM System PLOS ONE. ,vol. 10, pp. e0116218- ,(2015) , 10.1371/JOURNAL.PONE.0116218