Untersuchungen zur Pathogenese der Huntington-Krankheit in transgenen Tiermodellen

作者: Huu Phuc Nguyen

DOI:

关键词:

摘要:

参考文章(111)
Ants Kask, Huu Phuc Nguyen, Reinhard Pabst, Stephan von Hörsten, Factors influencing behavior of group-housed male rats in the social interaction test: focus on cohort removal. Physiology & Behavior. ,vol. 74, pp. 277- 282 ,(2001) , 10.1016/S0031-9384(01)00587-X
P. Hemachandra Reddy, Maya Williams, Vinod Charles, Lisa Garrett, Lisa Pike-Buchanan, William O. Whetsell, Georgina Miller, Danilo A. Tagle, Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA Nature Genetics. ,vol. 20, pp. 198- 202 ,(1998) , 10.1038/2510
Cheol-Koo Lee, Richard Weindruch, Tomas A. Prolla, Gene-expression profile of the ageing brain in mice. Nature Genetics. ,vol. 25, pp. 294- 297 ,(2000) , 10.1038/77046
Shi-Hua Li, Claire-Anne Gutekunst, Steven M. Hersch, Xiao-Jiang Li, Interaction of Huntingtin-Associated Protein with Dynactin P150Glued The Journal of Neuroscience. ,vol. 18, pp. 1261- 1269 ,(1998) , 10.1523/JNEUROSCI.18-04-01261.1998
Takayoshi Shimohata, Toshihiro Nakajima, Mitsunori Yamada, Chiharu Uchida, Osamu Onodera, Satoshi Naruse, Tetsuya Kimura, Reiji Koide, Kenkichi Nozaki, Yasuteru Sano, Hiroshi Ishiguro, Kumi Sakoe, Takayuki Ooshima, Aki Sato, Takeshi Ikeuchi, Mutsuo Oyake, Toshiya Sato, Yasuyuki Aoyagi, Isao Hozumi, Toshiharu Nagatsu, Yoshihisa Takiyama, Masatoyo Nishizawa, Jun Goto, Ichiro Kanazawa, Irwin Davidson, Naoko Tanese, Hitoshi Takahashi, Shoji Tsuji, Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription. Nature Genetics. ,vol. 26, pp. 29- 36 ,(2000) , 10.1038/79139
Ester Martı́n-Aparicio, Ai Yamamoto, Félix Hernández, René Hen, Jesús Avila, José J. Lucas, Proteasomal-Dependent Aggregate Reversal and Absence of Cell Death in a Conditional Mouse Model of Huntington's Disease The Journal of Neuroscience. ,vol. 21, pp. 8772- 8781 ,(2001) , 10.1523/JNEUROSCI.21-22-08772.2001
John M. Warrick, H.Y. Edwin Chan, Gladys L. Gray-Board, Yaohui Chai, Henry L. Paulson, Nancy M. Bonini, Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70. Nature Genetics. ,vol. 23, pp. 425- 428 ,(1999) , 10.1038/70532
Michael W. Schwartz, Stephen C. Woods, Daniel Porte, Randy J. Seeley, Denis G. Baskin, Central nervous system control of food intake Nature. ,vol. 404, pp. 661- 671 ,(2000) , 10.1038/35007534
MF Beal, E Brouillet, BG Jenkins, RJ Ferrante, NW Kowall, JM Miller, E Storey, R Srivastava, BR Rosen, BT Hyman, Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid The Journal of Neuroscience. ,vol. 13, pp. 4181- 4192 ,(1993) , 10.1523/JNEUROSCI.13-10-04181.1993
Roy B. Dyer, Cynthia T. McMurray, Mutant protein in Huntington disease is resistant to proteolysis in affected brain. Nature Genetics. ,vol. 29, pp. 270- 278 ,(2001) , 10.1038/NG745