Effectiveness of influenza vaccine when given during an outbreak of influenza A/H3N2 in a nursing home.

摘要: An explosive outbreak of influenza A/H3N2 began in a nursing home the Denver area early November, 1987. Residents had not been vaccinated at that time. Vaccine was administered on November 11th. Two weeks after vaccine given, attack rate differed between and unvaccinated individuals. There were 40 cases among 98 elderly residents, 12 pneumonia, seven deaths. efficacy two it given estimated to be 65.4% preventing clinical illness. no pneumonia deaths people who more than before. The virus identified as A by complement fixation tests with convalescent sera from 16 individuals ill. Many also hemagglutination inhibition titers for A/Colorado/1/87, which high A/Leningrad/87. A/Colorado/1/87 closely resembled A/Sichuan/87.