A preliminary comparative treatment planning study for radiotherapy of age-related maculopathy.

摘要: Abstract Purpose : We present a comparative planning of different approaches for external radiotherapy in age-related maculopathies. Materials and methods Calculated dose distributions dose–volume histograms (a) bilateral irradiation with 6 MV photons, (b) single lateral-oblique beam using either electrons or protons (c) an anterior circular proton beam. Results For lateral photon electron beams the to lens is usually lower than 10% macula. The entrance doses are about 50% which increase up 100% at orbital bone. About 5 mm optic nerves irradiated maximal while chiasma spared. A gives fellow eye. spares eye but rather inhomogeneous target volume. beam, 4 nerve receives 90% dose, skin least 70% macula An 1 isodose periphery lens. Conclusion Doses critical structures can be dramatically diminished all techniques by reducing size, only if very precise set-up used. Proton attractive solution, impact such choice on use facilities national health system should carefully evaluated, as well risk radio-induced secondary neoplasias.