Procedural Outcomes and Survival After Catheter Ablation of Ventricular Tachycardia in Relation to Electroanatomical Substrate in Patients With Nonischemic-Dilated Cardiomyopathy: The Role of Unipolar Voltage Mapping

摘要: Scar and Outcomes Of VT Ablation in Nonischemic DCM Introduction In patients with ischemic cardiomyopathy the size of bipolar low-voltage areas (LVA) electroanatomical maps (EAM) was associated poorer outcomes after catheter ablation (CA) ventricular tachycardia (VT). However, effect LVA on survival nonischemic dilated (NIDCM) has not been studied. Methods Results In 55 NIDCM (48 male, age 61 ± 16 years, ejection fraction 32 13%) an EAM to delineate unipolar LVAs performed 52 (94.5%) endocardially, 24 (43.6%) epicardially, 21 (38.2%) both surfaces. Additionally, activation mapping possible 22 (40%) patients. CA lines transecting scar targeting late potentials all Complete noninducibility at end achieved 40 (72.7%) During median follow-up (interquartile range IQR 6, 34) months, recurrences were observed 30 (54.5%) cardiac death 14 (25.5%) The ROC analysis revealed that endocardial ( 145 cm2 a predictor for (adjusted HR = 6.9; P 0.014) UVA ≥ 54% (of total LV surface) recurrence 3.5; 0.016). Conclusion The (<8.3 mV) strong independent mortality NIDCM.