Symptom Profiles, Health-Related Quality of Life, and Clinical Blood Markers among Korean Community-Dwelling Older Adults Living with Chronic Conditions.

摘要: Older adults suffer from multiple symptoms, which negatively affects their health-related quality of life. The single-symptom management approach has been less than effective. data 2362 Korean community-dwelling older aged 70 and above were analyzed in the Frailty Aging Cohort Study (KFACS) study. A cluster analysis, correlation logistic regression used to analyze data. We found three symptom clusters: high burden (HSB, n = 1032); pain fatigue group (PAF, 566); sleep deprivation (SDP, 764). Participants HSB are more likely be old age (OR 1.1), female 2.4), live a rural area 1.4), have low physical activity 0.9), chronic conditions 1.5). clinical blood markers analysis showed negative relationship among health, free T4 (r −0.083, p < 0.01) insulin −0.084, 0.01). sex-specific differences clusters. While testosterone (male: r 0.124, female: 0.110, 0.05) dehydroepiandrosterone (DHEA) 0.352 0.134, associated with health group, only was mental −0.093, −0.116, SDP group. These findings suggest potential role patient’s sex hormones symptoms adults. Understanding profiles impact biopsychosocial factors may enhance precision management.