作者: John W. Kusek , Terry Coyne , Ann de Velasco , Martin J. Drabik , R. Allan Finlay
DOI: 10.1016/0197-2456(93)90033-A
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摘要: Abstract The Modification of Diet in Renal Disease (MDRD) Study is a randomized, multicenter clinical trial testing the effects three different levels dietary protein and phosphorus intake two blood pressure control on rate loss kidney function persons with various chronic diseases. During 27-month recruitment period, 2507 who had objective evidence impaired were screened at 15 centers. Eight hundred forty men women aged 18–70 glomerular filtration between 13 55 ml/min/1.73 m 2 randomized. Medical record review was primary means identifying study participants beginning recruitment. Later, use mass media instrumental alerting both public medical community need for MDRD participants. Overall, most important sources randomized referral by personal physician (45.4%) relative/friend (5.6%), self-referral after hearing about from newspapers (23.9%) television (5.2%). Review records defined patient populations source 22.3% A total 9.4% called toll-free (800) telephone number before contacting