作者: Megan A. Rech , Elisabeth Donahey , Jacqueline M. Cappiello Dziedzic , Laura Oh , Elizabeth Greenhalgh
DOI: 10.1002/PHAR.1522
关键词:
摘要: Drug abuse is a common problem and growing concern in the United States, over past decade, novel or atypical drugs have emerged become increasingly popular. Recognition treatment of new pose many challenges for health care providers due to lack quantitative reporting routine surveillance, difficulty detection blood urine analyses. Furthermore, street manufacturers are able rapidly adapt develop synthetic isolates older as soon law enforcement agencies render them illegal. In this article, we describe clinical adverse effects purported pharmacology several classes including cannabinoids, cathinones, salvia, desomorphine, kratom. Because these substances can severe life-threatening effects, knowledge general toxicology key recognizing acute intoxication overdose; however, typical toxidromes (e.g., cholinergic, sympathomimetic, opioid, etc.) not precipitated by agents. Medical management patients who overdose on largely consists supportive care, although naloxone may be used an antidote desomorphine overdose. Symptoms aggression psychosis treated with sedation (benzodiazepines, propofol) antipsychotics (haloperidol agents such quetiapine ziprasidone). Other facets consider include withdrawal addiction, nutrition support, potential transmission infectious diseases.