Antiproliferative and overadditive effects of rapamycin and FTY720 in pancreatic cancer cells in vitro.
作者： Y. Shen , X. Wang , W. Xia , C. Wang , M. Cai
DOI: 10.1016/J.TRANSPROCEED.2008.03.150
关键词:
摘要: … of pancreatic carcinoma cells in a dose-dependent manner. The combined use of rapamycin and FTY720 showed additive and supra-additive antiproliferative effects on pancreatic …
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Peter J Houghton, Shile Huang, Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic. Current opinion in investigational drugs. ,vol. 3, pp. 295- 304 ,(2002)
Yoshiko Sonoda, Daisuke Yamamoto, Shinya Sakurai, Maki Hasegawa, Eriko Aizu-Yokota, Takashi Momoi, Tadashi Kasahara, None, FTY720, a novel immunosuppressive agent, induces apoptosis in human glioma cells. Biochemical and Biophysical Research Communications. ,vol. 281, pp. 282- 288 ,(2001) , 10.1006/BBRC.2001.4352
S. Stracke, L. Ramudo, F. Keller, D. Henne-Bruns, J.M. Mayer, Antiproliferative and overadditive effects of everolimus and mycophenolate mofetil in pancreas and lung cancer cells in vitro. 14th Annual Meeting of the German-Transplantation-Society. ,vol. 38, pp. 766- 770 ,(2006) , 10.1016/J.TRANSPROCEED.2006.01.030
Allan MacDonald, Joseph Scarola, James T. Burke, James J. Zimmerman, Clinical pharmacokinetics and therapeutic drug monitoring of sirolimus Clinical Therapeutics. ,vol. 22, ,(2000) , 10.1016/S0149-2918(00)89027-X
HARUHITO AZUMA, SHIRO TAKAHARA, SHIGEO HORIE, SATORU MUTO, YOSHINORI OTSUKI, YOJI KATSUOKA, Induction of Apoptosis in Human Bladder Cancer Cells In Vitro and In Vivo Caused by FTY720 Treatment The Journal of Urology. ,vol. 169, pp. 2372- 2377 ,(2003) , 10.1097/01.JU.0000064938.32318.91
Manuel Hidalgo, Eric K Rowinsky, The rapamycin-sensitive signal transduction pathway as a target for cancer therapy Oncogene. ,vol. 19, pp. 6680- 6686 ,(2000) , 10.1038/SJ.ONC.1204091
Naotsugu Ichimaru, Yoji Katsuoka, Norio Nonomura, Haruhito Azuma, Seiichi Suzuki, Akihiko Okuyama, Yoshinori Otsuki, Shiro Takahara, Ryosuke Fukui, Masaaki Hoshiga, Junji Morimoto, Tadashi Ishihara, Yuko Itoh, Jing Ding Wang, Marked Prevention of Tumor Growth and Metastasis by a Novel Immunosuppressive Agent, FTY720, in Mouse Breast Cancer Models Cancer Research. ,vol. 62, pp. 1410- 1419 ,(2002)
Howard J. Eisen, E. Murat Tuzcu, Richard Dorent, Jon Kobashigawa, Donna Mancini, Hannah A. Valantine-von Kaeppler, Randall C. Starling, Keld Sørensen, Manfred Hummel, Joan M. Lind, Kamal H. Abeywickrama, Peter Bernhardt, Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients. The New England Journal of Medicine. ,vol. 349, pp. 847- 858 ,(2003) , 10.1056/NEJMOA022171
Jordan D. Berlin, Paul Catalano, James P. Thomas, John W. Kugler, Daniel G. Haller, Al Bowen Benson, Phase III Study of Gemcitabine in Combination With Fluorouracil Versus Gemcitabine Alone in Patients With Advanced Pancreatic Carcinoma: Eastern Cooperative Oncology Group Trial E2297 Journal of Clinical Oncology. ,vol. 20, pp. 3270- 3275 ,(2002) , 10.1200/JCO.2002.11.149
Anne Boulay, Sabine Zumstein-Mecker, Christine Stephan, Iwan Beuvink, Frederic Zilbermann, Roland Haller, Sonja Tobler, Christoph Heusser, Terence O’Reilly, Barbara Stolz, Andreas Marti, George Thomas, Heidi A. Lane, Antitumor Efficacy of Intermittent Treatment Schedules with the Rapamycin Derivative RAD001 Correlates with Prolonged Inactivation of Ribosomal Protein S6 Kinase 1 in Peripheral Blood Mononuclear Cells Cancer Research. ,vol. 64, pp. 252- 261 ,(2004) , 10.1158/0008-5472.CAN-3554-2