The cell biology of mitotic recombination in Saccharomyces cerevisiae

作者: Michael Lisby , Rodney Rothstein

DOI: 10.1007/978-3-540-71021-9_11

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摘要: Genetic recombination relies on a number of biochemical activities that must be present at the right time and place in order for two DNA molecules to recombined properly. Recent advances real-time fluorescence microscopy provide us with glimpse homologous taking living cells. These approaches reveal is highly choreographed vivo its spatio-temporal organization being dependent both cell cycle phase nature initiating lesion. In this chapter, we review biology mitotic cells main focus yeast Saccharomyces cerevisiae but also drawing parallels other eukaryotic organisms.

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