A new technique for unbiased external ion accumulation in a quadrupole two-dimensional ion trap for electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.
作者： Mikhail E. Belov , Evgenii N. Nikolaev , Kim Alving , Richard D. Smith
DOI: 10.1002/RCM.356
关键词:
摘要: External ion accumulation in a two-dimensional (2D) multipole trap has been shown to increase the sensitivity, dynamic range and duty cycle of Fourier transform cyclotron resonance (FTICR) mass spectrometer. However, it is important that trapped ions be detected without significant bias at longer times external 2D trap. With increasing time pronounced m/z discrimination was observed when trapping an quadrupole. In this work we show superimposing lower rf-amplitude dipolar excitation over main rf-field quadrupole results disruption can potentially used achieve unbiased with FTICR. Copyright © 2001 John Wiley & Sons, Ltd.
harvard.edu
sci-hub.se 参考文章(30)
Dieter Gerlich, Inhomogeneous RF Fields: A Versatile Tool for the Study of Processes with Slow Ions Advances in Chemical Physics. ,vol. 82, pp. 1- 176 ,(2007) , 10.1002/9780470141397.CH1
H.G. Dehmelt, Radiofrequency Spectroscopy of Stored Ions I: Storage Advances in atomic and molecular physics. ,vol. 3, pp. 53- 72 ,(1968) , 10.1016/S0065-2199(08)60170-0
C. Schwebel, P.A. Môller, Pham Tu Manh, Formation et confinement d'ions multicharges dans un champ quadrupolaire a haute fréquence Revue de Physique Appliquée. ,vol. 10, pp. 227- 239 ,(1975) , 10.1051/RPHYSAP:01975001004022700
Michael W. Senko, Christopher L. Hendrickson, Mark R. Emmett, Stone D. H. Shi, Alan G. Marshall, External accumulation of ions for enhanced electrospray ionization fourier transform ion cyclotron resonance mass spectrometry Journal of the American Society for Mass Spectrometry. ,vol. 8, pp. 970- 976 ,(1997) , 10.1016/S1044-0305(97)00126-8
J.-C. Mathurin, S. Grégoire, A. Brunot, J.-C. Tabet, R. E. March, S. Catinella, P. Traldi, Investigation of Space Charge Interactions Which Arise During Simultaneous Confinement of Positive and Negative Ions in an Ion Trap Mass Spectrometer Journal of Mass Spectrometry. ,vol. 32, pp. 829- 837 ,(1997) , 10.1002/(SICI)1096-9888(199708)32:8<829::AID-JMS539>3.0.CO;2-X
M. A. N. Razvi, X. Z. Chu, R. Alheit, G. Werth, R. Blümel, Fractional frequency collective parametric resonances of an ion cloud in a Paul trap Physical Review A. ,vol. 58, pp. 34- 37 ,(1998) , 10.1103/PHYSREVA.58.R34
Byungchul Cha, Michael Blades, D. J. Douglas, An Interface with a Linear Quadrupole Ion Guide for an Electrospray-Ion Trap Mass Spectrometer System Analytical Chemistry. ,vol. 72, pp. 5647- 5654 ,(2000) , 10.1021/AC0004862
Mikhail E. Belov, Evgenii N. Nikolaev, Gordon A. Anderson, Kenneth J. Auberry, Richard Harkewicz, Richard D. Smith, Electrospray ionization-Fourier transform ion cyclotron mass spectrometry using ion preselection and external accumulation for ultrahigh sensitivity Journal of the American Society for Mass Spectrometry. ,vol. 12, pp. 38- 48 ,(2001) , 10.1016/S1044-0305(00)00198-7
Kristin Sannes-Lowery, Steven A. Hofstadler, Characterization of multipole storage assisted dissociation: implications for electrospray ionization mass spectrometry characterization of biomolecules. Journal of the American Society for Mass Spectrometry. ,vol. 11, pp. 1- 9 ,(2000) , 10.1016/S1044-0305(99)00110-5
Mikhail E. Belov, Mikhail V. Gorshkov, Harold R. Udseth, Gordon A. Anderson, Richard D. Smith, Zeptomole-sensitivity electrospray ionization--Fourier transform ion cyclotron resonance mass spectrometry of proteins. Analytical Chemistry. ,vol. 72, pp. 2271- 2279 ,(2000) , 10.1021/AC991360B