Isatin derivatives, pharmaceutical compositions thereof, and methods of use thereof
作者： Christopher Lincoln , Jun Xie , Sangkil Nam , Larry Overman , David A. Horne
DOI:
关键词:
摘要: One aspect of the invention relates to novel isatin derivative compounds and pharmaceutical composition thereof. Another methods using disclosed herein compositions In certain embodiments, method is used treat a cancer or tumor in subject including, without limitation, prostate cancer, melanoma, pancreatic ovarian lymphoma. embodiment, condition that can be regulated by activation one more proteins such as EGFR, Erk1/2, Her2/Neu, Jak2, Src, Stat3, Akt, Cyclin B1, Cdc25C. disruption microtubule formations.
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