Drug Suspension Development for the Back of the Eye
作者： Jithan Aukunuru , Puneet Tyagi , Chandrasekar Durairaj , Uday B Kompella , None
DOI: 10.1007/978-1-4419-9920-7_18
关键词:
摘要: With the FDA approval of triamcinolone acetonide suspensions for intravitreal injections, there is renewed interest in developing drug sustained delivery. For back eye delivery, can potentially be administered by various other routes including periocular, retrobulbar, and suprachoroidal routes. Suspension development, although new not new, especially topical, oral, parenteral dosage forms. This chapter summarizes principles suspension-based delivery suspension formulation. Further, it highlights some unique issues related to product development.
springer.com
sci-hub.st 参考文章(30)
Henry F. Edelhauser, Dayle H. Geroski, Drug delivery for posterior segment eye disease. Investigative Ophthalmology & Visual Science. ,vol. 41, pp. 961- 964 ,(2000)
Tsutomu Yasukawa, Yuichiro Ogura, Medical Devices for the Treatment of Eye Diseases Drug Delivery. ,vol. 197, pp. 469- 489 ,(2010) , 10.1007/978-3-642-00477-3_16
A A Souza-Filho, A G Oliveira, J A Cardillo, Intravitreal Bioerudivel sustained-release triamcinolone microspheres system (RETAAC). Preliminary report of its potential usefulnes for the treatment of diabetic macular edema. Archivos de la Sociedad Espanola de Oftalmologia. ,vol. 81, pp. 675- 681 ,(2006)
A. A. Silva Jurnior, A. A. S. Lima filho, A. G. Oliveira, R. Belfort, D. Lavinsky, R. Costa, J. A. Cardillo, Phase I/II Study of Intravitreal Triamcinolone Acetonide Microspheres for Treatment of Diffuse Diabetic Macular Edema Unresponsive to Conventional Laser Photocoagulation Treatment Investigative Ophthalmology & Visual Science. ,vol. 49, pp. 2698- 2698 ,(2008)
Howard C. Ansel, Loyd V. Allen, Nicholas G. Popovich, Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems ,(2004)
Alfonso R. Gennaro, Remington: The Science and Practice of Pharmacy ,(2003)
Yi-Sheng Chang, Chao-Liang Wu, Sung-Huei Tseng, Pao-Ying Kuo, Shih-Ya Tseng, Cytotoxicity of Triamcinolone Acetonide on Human Retinal Pigment Epithelial Cells Investigative Opthalmology & Visual Science. ,vol. 48, pp. 2792- 2798 ,(2007) , 10.1167/IOVS.06-1146
Chandrasekar Durairaj, Stephen J. Kim, Henry F. Edelhauser, Jaymin C. Shah, Uday B. Kompella, Influence of Dosage Form on the Intravitreal Pharmacokinetics of Diclofenac Investigative Ophthalmology & Visual Science. ,vol. 50, pp. 4887- 4897 ,(2009) , 10.1167/IOVS.09-3565
Polly A. Quiram, Christine R. Gonzales, Steven D. Schwartz, Severe steroid-induced glaucoma following intravitreal injection of triamcinolone acetonide. American Journal of Ophthalmology. ,vol. 141, pp. 580- 582 ,(2006) , 10.1016/J.AJO.2005.10.004
John T. Thompson, Cataract formation and other complications of intravitreal triamcinolone for macular edema. American Journal of Ophthalmology. ,vol. 141, pp. 629- 637 ,(2006) , 10.1016/J.AJO.2005.11.050