摘要: Tremendous progress in the ability to predict outcome patients with cutaneous melanoma has come about through careful prospective studies of clinical and histopathologic features primary tumors. Observations biologic behavior seem be generalizable over wide geographic areas. For example, tumor Australia appears similar that observed United States which turn for light skin Europeans. Awareness these prognostic factors allow physician categorize into low, indeterminate, high risk groups. This facilitates 1) patient counselling; 2) matching extent surgery severity tumor; 3) construction groups comparable evaluation therapeutic (adjuvant) trials; 4) understanding tumor.