Association of cdk2 kinase with the transcription factor E2F during S phase
作者： M Pagano , G Draetta , P Jansen-Durr
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摘要: The transcription factor E2F controls the expression of several proliferation-related genes and is a target adenovirus E1A oncogene. In human cells, both cyclin A cdk2 protein kinase were found in complexes with E2F. Although total amounts constant cell cycle, binding to was detected only when cells entered S phase, time activated. These data suggest that interaction between requires an active has as targeting component.
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