Coronary Heart Disease in HIV-Infected Patients: Epidemiology

作者: M. Mary-Krause , D. Costagliola

DOI: 10.1007/978-88-470-0761-1_8

关键词:

摘要: Cardiovascular disease continues to be the leading cause of death among general population industrialized countries. It is also main reason for hospitalization. But what about HIV-infected subjects? With advent combination antiretroviral therapy (cART) HIV infection, including protease inhibitors (PIs), in April 1996 France, morbidity AIDS-defining illnesses has been reduced and patients are living longer [1, 2]. Thus, spectrum diseases related shifting from opportunistic towards long-term complications such as cancers, coinfection with other viruses hepatitis C virus, metabolic effects cART. Some these disorders potential risk factors cardiovascular so could lead over-mortality over-morbidity. currently account 7% deaths subjects 14% non-HIV-related [3], 16% a good immunovirologic response cART [4].

参考文章(57)
Staszewski S, Brodt H, Rickerts, Stille W, Incidence of myocardial infarctions in HIV-infected patients between 1983 and 1998: the Frankfurt HIV-cohort study. European Journal of Medical Research. ,vol. 5, pp. 329- ,(2000)
Strategies for Management of Antiretroviral Therapy (SMART) Study Group, None, CD4+ count-guided interruption of antiretroviral treatment. The New England Journal of Medicine. ,vol. 355, pp. 2283- 2296 ,(2006) , 10.1056/NEJMOA062360
Class of antiretroviral drugs and the risk of myocardial infarction. The New England Journal of Medicine. ,vol. 356, pp. 1723- 1735 ,(2007) , 10.1056/NEJMOA062744
Megan E Shoff, Charlotte E Joslin, Elmer Y Tu, Laura Kubatko, Paul A Fuerst, Efficacy of contact lens systems against recent clinical and tap water Acanthamoeba isolates. Cornea. ,vol. 27, pp. 713- 719 ,(2008) , 10.1097/QAI.0B013E31815E7251
Bruno Gallet, Marc Pulik, Philippe Genet, Pierre Chedin, Michel Hiltgen, Vascular complications associated with use of HIV protease inhibitors. The Lancet. ,vol. 351, pp. 1958- 1959 ,(1998) , 10.1016/S0140-6736(05)78643-8
Sharon Safrin, Carl Grunfeld, Fat distribution and metabolic changes in patients with HIV infection AIDS. ,vol. 13, pp. 2493- 2505 ,(1999) , 10.1097/00002030-199912240-00002
Andrew Carr, Katherine Samaras, Anna Thorisdottir, Gilbert R Kaufmann, Donald J Chisholm, David A Cooper, Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: acohort study The Lancet. ,vol. 353, pp. 2093- 2099 ,(1999) , 10.1016/S0140-6736(98)08468-2
Samuel A. Bozzette, Christopher F. Ake, Henry K. Tam, Sophia W. Chang, Thomas A. Louis, Cardiovascular and cerebrovascular events in patients treated for human immunodeficiency virus infection. The New England Journal of Medicine. ,vol. 348, pp. 702- 710 ,(2003) , 10.1056/NEJMOA022048