Antibodies and chimeric antigen receptors specific for ror1
作者： Jui Dutta-Simmons , Yan Chen , Steven M. Shamah , Csaba Pazmany
DOI:
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摘要: Provided are ROR1 binding molecules, including anti-ROR1 antibodies, antibody fragments such as variable heavy chain (VH) regions, single-chain fragments, and chimeric receptors the antigen (CARs). In some embodiments, antibodies specifically bind to ROR1. Among human those that compete for with reference a non-human antibody. Also provided genetically engineered cells expressing receptors, uses of molecules adoptive cell therapy.
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