Free estradiol and sex hormone-binding globulin.

作者: William Rosner

DOI: 10.1016/J.STEROIDS.2014.08.005

关键词:

摘要: SHBG is a plasma protein that participates in the regulation of free estradiol and testosterone plasma. We discuss concept nature how best to ascertain its value. It can be measured or calculated; ways which this done are explored along with advantages disadvantages each.

参考文章(28)
G.L. Hammond, J.A. Nisker, L.A. Jones, P.K. Siiteri, Estimation of the percentage of free steroid in undiluted serum by centrifugal ultrafiltration-dialysis. Journal of Biological Chemistry. ,vol. 255, pp. 5023- 5026 ,(1980) , 10.1016/S0021-9258(19)70742-X
M. SAEED KHAN, BARBARA B. KNOWLES, DAVID P. ADEN, ROSNE ROSNE, SECRETION OF TESTOSTERONE-ESTRADIOL-BINDING GLOBULIN BY A HUMAN HEPATOMA-DERIVED CELL LINE The Journal of Clinical Endocrinology and Metabolism. ,vol. 53, pp. 448- 449 ,(1981) , 10.1210/JCEM-53-2-448
Jennifer S. Hackbarth, Jonathan B. Hoyne, Stefan K. Grebe, Ravinder J. Singh, Accuracy of calculated free testosterone differs between equations and depends on gender and SHBG concentration. Steroids. ,vol. 76, pp. 48- 55 ,(2011) , 10.1016/J.STEROIDS.2010.08.008
Yuanyuan Ma, Dongming Liang, Jian Liu, Jian-Guo Wen, Einar Servoll, Gudmund Waaler, Thorstein Sæter, Karol Axcrona, Ljiljana Vlatkovic, Ulrika Axcrona, Elisabeth Paus, Yue Yang, Zhiqian Zhang, Gunnar Kvalheim, Jahn M. Nesland, Zhenhe Suo, SHBG Is an Important Factor in Stemness Induction of Cells by DHT In Vitro and Associated with Poor Clinical Features of Prostate Carcinomas PLoS ONE. ,vol. 8, pp. e70558- ,(2013) , 10.1371/JOURNAL.PONE.0070558
Markus Thaler, Carolin Müller, Alice Schlichtiger, Katharina Gründler, Melanie Moore, Peter B. Luppa, Steroid binding properties of the 2nd WHO International Standard for sex hormone-binding globulin. Clinical Chemistry and Laboratory Medicine. ,vol. 49, pp. 869- 872 ,(2011) , 10.1515/CCLM.2011.146
Ragnar Södergard, Torbjörn Bäckström, Vasant Shanbhag, Hans Carstensen, Calculation of free and bound fractions of testosterone and estradiol-17β to human plasma proteins at body temperature Journal of Steroid Biochemistry. ,vol. 16, pp. 801- 810 ,(1982) , 10.1016/0022-4731(82)90038-3
James D. Faix, Principles and pitfalls of free hormone measurements Best Practice & Research Clinical Endocrinology & Metabolism. ,vol. 27, pp. 631- 645 ,(2013) , 10.1016/J.BEEM.2013.06.007
M. Dowsett, M.D. Mansfield, D.J. Griggs, S.L. Jeffcoate, Validation and use of centrifugal ultrafiltration-dialysis in the measurement of percent free oestradiol in serum Journal of Steroid Biochemistry. ,vol. 21, pp. 343- 345 ,(1984) , 10.1016/0022-4731(84)90290-5
Julie A. Ray, Mark M. Kushnir, Ashley Bunker, Alan L. Rockwood, A. Wayne Meikle, Direct measurement of free estradiol in human serum by equilibrium dialysis–liquid chromatography–tandem mass spectrometry and reference intervals of free estradiol in women Clinica Chimica Acta. ,vol. 413, pp. 1008- 1014 ,(2012) , 10.1016/J.CCA.2012.02.028