In vivo 1H MRS of normal breast and breast tumors using a dedicated double breast coil.

作者: Ingrid S. Gribbestad , Trond E. Singstad , Gunnar Nilsen , Hans E. Fjøsne , Terje Engan

DOI: 10.1002/JMRI.1880080602

关键词:

摘要: Image-guided localized proton MR spectroscopy (MRS) of normal breasts and breast tumors (ductal undifferentiated carcinomas) was performed using a dedicated double coil. In vivo 1H spectra from 10 volunteers showed signals water lipids only, even in with small contribution fatty tissue. the 6 12 examined patients, an intense signal assigned to choline compounds detected. The also detected at lower levels remaining patients. This study shows that MRI/MRS examinations can be within examination time 45 60 minutes. Signals tumor metabolites may MRS.

参考文章(16)
Ingrid S. Gribbestad, Gunnar Nilsen, Hans Fj⊘sne, Reidun Fougner, Olav A. Haugen, Steffen B. Petersen, Peter A. Rinck, Stener Kvinnsland, Contrast-enhanced magnetic resonance imaging of the breast. Acta Oncologica. ,vol. 31, pp. 833- 842 ,(1992) , 10.3109/02841869209089715
D A Porter, N A Dobbs, P E Graves, M A Smith, M A Richards, C J Twelves, M Lowry, Phosphorus-31 metabolism of human breast—an in vivo magnetic resonance spectroscopic study at 1.5 Tesla British Journal of Radiology. ,vol. 67, pp. 36- 45 ,(1994) , 10.1259/0007-1285-67-793-36
CJ Twelves, DA Porter, M Lowry, NA Dobbs, PE Graves, MA Smith, RD Rubens, MA Richards, Phosphorus-31 metabolism of post-menopausal breast cancer studied in vivo by magnetic resonance spectroscopy. British Journal of Cancer. ,vol. 69, pp. 1151- 1156 ,(1994) , 10.1038/BJC.1994.226
Steven L. Patt, Brian D. Sykes, Water Eliminated Fourier Transform NMR Spectroscopy Journal of Chemical Physics. ,vol. 56, pp. 3182- 3184 ,(1972) , 10.1063/1.1677669
P E Sijens, H K Wijrdeman, M A Moerland, C J Bakker, J W Vermeulen, P R Luyten, Human breast cancer in vivo: H-1 and P-31 MR spectroscopy at 1.5 T. Radiology. ,vol. 169, pp. 615- 620 ,(1988) , 10.1148/RADIOLOGY.169.3.2847230
J Glaholm, M.O Leach, D.J Collins, J Mansi, I.C Sharp, A Madden, I.E Smith, V.R Mccready, In-vivo 31P magnetic resonance spectroscopy for monitoring treatment response in breast cancer. The Lancet. ,vol. 333, pp. 1326- 1327 ,(1989) , 10.1016/S0140-6736(89)92717-7
TAD Smith, J Glaholm, MO Leach, L Machin, DJ Collins, GS Payne, VR McCready, A comparison of in vivo and in vitro 31P NMR spectra from human breast tumours: variations in phospholipid metabolism. British Journal of Cancer. ,vol. 63, pp. 514- 516 ,(1991) , 10.1038/BJC.1991.122
PAUL A. BOTTOMLEY, Spatial localization in NMR spectroscopy in vivo. Annals of the New York Academy of Sciences. ,vol. 508, pp. 333- 348 ,(1987) , 10.1111/J.1749-6632.1987.TB32915.X