Using optical coherence tomography to rapidly phenotype and quantify congenital heart defects associated with prenatal alcohol exposure.

摘要: Background The most commonly used method to analyze congenital heart defects involves serial sectioning and histology. However, this is often a time-consuming process where the quantification of cardiac can be difficult due problems with accurate section registration. Here we demonstrate advantages using optical coherence tomography, comparatively new rising technology, phenotype avian embryo hearts in model Fetal Alcohol Syndrome binge-like quantity alcohol/ethanol was introduced at gastrulation.