Postoperative Intra-abdominal Pressure and Renal Function After Liver Transplantation

作者: Gianni Biancofiore

DOI: 10.1001/ARCHSURG.138.7.703

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摘要: Hypothesis Intra-abdominal hypertension frequently threatens renal function early after orthotopic liver transplantation (OLT). Design A prospective study of consecutive patients who underwent OLT. Setting The intensive care unit a National Health Service teaching hospital. Patients and Main Outcome Measures intra-abdominal pressure (IAP) 108 OLT was postoperatively measured 3 times day for 72 hours using the urinary bladder technique. defined as an IAP 25 mm Hg or higher. Results Thirty-four (31%) had high IAP. Acute failure developed in 17 recipients (16%), 11 (65%) whom ( P .01), with mean ± SD 27.9 9.9 vs 18.6 5.2 those without acute .001). subjects were more administered loop diuretics to maintain adequate diuresis .001) low arterial on surgery despite fact that they given intravenous fluids .01) did not differ need inotropic drugs. Logistic regression analysis showed intraoperative transfusions than 15 U, respiratory failure, independent risk factors failure. length stay similar normal IAP, but mortality higher among latter = .02). Conclusions is common significantly associated reduced output, mortality. It is, therefore, worth monitoring undergoing

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