Molecular Pathology and Diagnostics of Gynecologic Malignancies

摘要: Gynecologic malignancies account for roughly 13 % of solid tissue tumors in women. Many these malignancies, such as many ovarian tumors, first present at an advanced stage, making them difficult to treat. Until recently the analysis was largely limited hematoxylin-eosin-stained slide examination, supplemented with immunohistochemical stains. Recently, molecular diagnostic techniques have been applied some success, especially BRCA1/2 mutations and Lynch syndrome analyses. Here, we describe tests gynecologic discuss possible future developments this field.