Biomarkers in assessing tubular lesions of the solitary kidney. The solitary kidney in special conditions.

摘要: The paper highlights the importance of tubular lesions solitary kidney (SK), identified and monitored by means urinary biomarkers, mainly N-acetyl-beta-D-glucosaminidase (NAG), albumin, alpha 1-, beta 2-microglobulin. It is considered that assessment a SK should be performed with four not three parameters as it was usually done until recently: renal function, proteinuria blood pressure (BP), to which biomarkers added. can result after nephrectomy for transplantation. In some countries living donors represent only option performing in has generally good evolution, although sometimes injury manifested proteinuria, arterial hypertension (AH), or diminution function does occur. Therefore, require attentive monitoring. have evolution (even donors), spite alterations above-mentioned clinical biological parameters. very infrequent cases who evolve progressively towards failure are predictable, requires monitoring all persons SK. represents special situation case association disease affecting kidney, such tract infection (UTI), diabetes mellitus, systemic lupus erythematosus (SLE). Pregnancy occurring person wi th also needs follow-up. associated diseases, preeclampsia patients SK, impose appropriate therapeutic behaviour. remains particular entity nephrology carefully monitored. adaptative phenomena (SK) accompanied (AH) Glomerular Filtration Rate (GFR), constituting triad Tubular encountered could evaluated adding valuable tool these patients. practice raises problems, both practical ethical ones. We view donors. take into account its other mellitus pregnancy.