Prevention of Venous Thromboembolism in the ICU

摘要: Background Although venous thromboembolism (VTE) is an important cause of morbidity and mortality in critical care unit patients, the risk VTE its prevention have been poorly characterized this population. Evidence-based thromboprophylaxis guidelines are also not available for these critically ill patients. Objectives To review prevalence VTE, to summarize clinical trials thromboprophylaxis, outline a practical approach Methods Systematic relevant literature. Results Most patients units at least one major factor many multiple factors. Objectively confirmed deep-vein thrombosis (DVT) rates varied from 13 31% among four prospective studies which did receive prophylaxis. We were able identify only three randomized conducted units. The results suggest that both low-dose heparin low-molecular-weight efficacious preventing DVT compared with no Fourteen reported compliance some form occurred 33 100% Conclusions There paucity data assessing risks settings. Selection prophylaxis challenging involves consideration thromboembolic bleeding risks, may vary same patient day day.