PET Imaging in Glioblastoma: Use in Clinical Practice

摘要: ABSTRACT Positron emission tomography (PET) is a nuclear medicine imaging method with increasing relevance for the diagnosis, prognostication, and monitoring of glioblastomas. PET provides additional insight beyond magnetic resonance (MRI) into biology gliomas, which can be used noninvasive grading, differential delineation tumor extent, planning surgery, radiotherapy post-treatment monitoring. In clinical practice, two classes radiotracers have been predominantly purposes, namely glucose metabolism tracers amino acid transport tracers. Both provide information on grading prognosis but tracers, exhibit lower uptake in normal brain tissue, are better suited treatment planning, or follow-up than 18F-2-fluoro- 2-deoxy-D-glucose (18F-FDG). Owing to progress using radiolabeled acids recent years, Response Assessment Neuro-Oncology (RANO) working group, an international effort develop new standardized response criteria trials tumors, has recently recommended as tool diagnostic assessment tumors. These developments well multimodality should improve these