Management of Locally Advanced Adenocarcinoma of the Esophagus and Gastroesophageal Junction: Finally a Consensus

摘要: Opinion statement: Adenocarcinoma of the esophagus is increasing in incidence Western nations leading to increased interest and opportunity study optimal management. Randomized trials have now robustly demonstrated preoperative therapy with chemoradiotherapy chemotherapy alone improves survival outcome for bulk curable patients, those locally advanced T1N1M0 T2-3 N0-1 M0 disease. Evidence suggests but does not confirm that radiation-containing regimens are more beneficial. Clinical staging designed exclude patients T1N0M0 disease who may be treated surgery metastatic benefit from intensive local therapy. The approach clinical includes endoscopy ultrasound fine needle aspirate assess regional disease, supplemented by CT PET scanning primarily Minimally invasive approaches esophagectomy used goal reducing complications, there no evidence mortality or ultimate improved.