New therapeutics in promoting and modulating mandibular growth in cases with mandibular hypoplasia.

摘要: Children with mandibular growth deficiency may develop airway obstruction. The standard treatment of severe obstruction involves invasive procedures such as tracheostomy. Mandibular distraction osteogenesis has been proposed in neonates a option to avoid tracheostomy procedure later life. Both and suffer from substantial shortcomings including scarring, unpredictability, surgical complications. Forward jaw positioning appliances have also used enhance mandible growth. However, the effectiveness these is limited lacks predictability. Current future approaches growth, both experimental clinical trials, their are presented discussed.