Autoimmunity in 2019

摘要: Based on the PubMed data, we have been performing a yearly evaluation of publications related to autoimmune diseases and immunology ascertain relative weight former in scientific literature. It is particularly intriguing observe that despite numerous new avenues immune-related mechanisms, such as cancer immunotherapy, proportion manuscripts autoimmunity continues increase has approaching 20% 2019. As previous 13 years, performed an arbitrary selection peer-reviewed articles published by major dedicated Journals discussed common themes which continue outnumber peculiarites diseases. The investigated areas included systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), psoriatic (PsA), autoantibodies (autoAbs), therapeutic novel pathogenic mechanisms for conditions. Some examples include pathogenetic evidence well represented IL21 or P2X7 receptor (P2X7R) SLE application single-cell RNA sequencing (scRNA-seq), mass cytometry, bulk (RNA-seq), flow cytometry analysis different cellular populations RA. Cumulatively interest clinicians, large number findings underline importance strict relationship between basic clinical science define developments. pipeline grow maintain constant molecules, illustrated RA PsA, this most certainly derived from high-throughput tools applied