Induced polymersome formation from a diblock PS-b-PAA polymer via encapsulation of positively charged proteins and peptides

作者: David Hvasanov , Jörg Wiedenmann , Filip Braet , Pall Thordarson

DOI: 10.1039/C1CC11662B

关键词:

摘要: In contrast to simple salts or negatively charged macromolecules, positively proteins and peptides including cytochrome c (yeast) poly-L-lysine are efficiently encapsulated while inducing the formation of polymersomes from polystyrene140-b-poly(acrylic acid)48 (PS140-b-PAA48).

参考文章(24)
A. Choucair, A. Eisenberg, Control of amphiphilic block copolymer morphologies using solution conditions. European Physical Journal E. ,vol. 10, pp. 37- 44 ,(2003) , 10.1140/EPJE/E2003-00002-5
Neil S Cameron, Muriel K Corbierre, Adi Eisenberg, 1998 E.W.R. Steacie Award Lecture Asymmetric amphiphilic block copolymers in solution: a morphological wonderland Canadian Journal of Chemistry. ,vol. 77, pp. 1311- 1326 ,(1999) , 10.1139/V99-141
Marc A. Gauthier, Harm-Anton Klok, Polymer–protein conjugates: an enzymatic activity perspective Polymer Chemistry. ,vol. 1, pp. 1352- 1373 ,(2010) , 10.1039/C0PY90001J
Patrick Lim Soo, Adi Eisenberg, Preparation of block copolymer vesicles in solution Journal of Polymer Science Part B. ,vol. 42, pp. 923- 938 ,(2004) , 10.1002/POLB.10739
Lie Ma, Adi Eisenberg, Relationship between wall thickness and size in block copolymer vesicles. Langmuir. ,vol. 25, pp. 13730- 13736 ,(2009) , 10.1021/LA9012729
Jeeyoung Choi, Michael F. Rubner, Influence of the Degree of Ionization on Weak Polyelectrolyte Multilayer Assembly Macromolecules. ,vol. 38, pp. 116- 124 ,(2005) , 10.1021/MA048596O
Peter Walde, Sosaku Ichikawa, Enzymes inside lipid vesicles: preparation, reactivity and applications. Biomolecular Engineering. ,vol. 18, pp. 143- 177 ,(2001) , 10.1016/S1389-0344(01)00088-0
Yisong Yu, Lifeng Zhang, Adi Eisenberg, Multiple Morphologies of Crew-Cut Aggregates of Polybutadiene-b-poly(acrylic acid) Diblocks with Low Tg Cores Langmuir. ,vol. 13, pp. 2578- 2581 ,(1997) , 10.1021/LA961058N
C D’Angelo, A Denzel, A Vogt, MV Matz, F Oswald, A Salih, GU Nienhaus, J Wiedenmann, Blue light regulation of host pigment in reef-building corals Marine Ecology Progress Series. ,vol. 364, pp. 97- 106 ,(2008) , 10.3354/MEPS07588