A Conjugated Polyelectrolyte with Pendant High Dense Short-Alkyl-Chain-Bridged Cationic Ions: Analyte-Induced Light-Up and Label-Free Fluorescent Sensing of Tumor Markers
作者： , , , ,
DOI: 10.3390/POLYM9060227
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摘要: A novel cationic water-soluble conjugated polyelectrolyte (CPE) of polyfluorene that contains 15% fraction 2,1,3-benzothiadiazole (BT) units (PFC3NBT) has been obtained. PFC3NBT demonstrates intramolecular energy transfer from the fluorene segments to BT sites when negatively charged species (SDS or DNAs) are added, following by a shift in emission color blue green, developed. The high density positive charges and pendent short alkyl chains N-propyltrimethylammoniums endow with solubility fluorescence quantum efficiency 33.6% water. properties were investigated presence adverse buffer solutions, different surfactants DNA strands. Interesting quenching at wavelength resonance (FRET) induced light-on observed discussed detail. Very previous reports, spectra transition happens an enhancement integrated fluorescent intensity. analytes light-up sensing system was studied PFC3NBT/SDS complex mode confirmed DNA/DNA-FAM systems. More exciting preliminary results on label-free tumor markers also reported investigating unique response 11 kinds proteins. These provide new insight view for designing CPEs features biomolecular sensing.
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