Electroporation and iontophoresis apparatus and method for insertion of drugs and genes into cells

作者: Lois J. Crandell , Gunter A. Hofmann

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摘要: A catheter device having a plurality of axially extending, circumferentially spaced electrodes carried thereby, infusion means for fluid medium carrying genes and drugs, expandable sealing at each end the off confining therapeutic to area be treated is inserted into selected blood vessel patient advanced preselected location within where cells on or near wall are treated. Once in place, expanded so that thereby contact with inner seals expand seal location. quantity drugs infused via tube conventional pump. power pack connected energized subjecting electric fields predetermined amplitude duration making walls transiently permeable enabling by enter without killing them.

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