COMPOSITIONS AND METHODS FOR THE TREATMENT OF ADDICTION, PSYCHIATRIC DISORDERS, AND NEURODEGENERATIVE DISEASE

摘要: The present invention is based, in part, on our discovery that certain types of therapeutic agents may be used combination to treat a variety neuropsychiatric and related disorders, including addiction (e.g., substance or activity) as well alleviate some symptoms associated with other diseases conditions. Regardless precise formulation, the compositions include one ingredient targets hypothalamo-pituitary- adrenal (HPA) axis at least active prefrontal cortex. Either both these combined an agent inhibits activity sympathetic nervous system. Thus, pharmacotherapies can also beta-adrenergic receptor otherwise acts antihypertensive anxiolytic agent. includes treatment cocaine-use disorder metyrapone oxazepam, while avoiding serious adverse events reducing likelihood relapse by blunting Cortisol increase stress cocaine use.