Vascularization Pattern in Hypertrophic Scars and Keloids: A Stereological Analysis

作者: Thaís Amadeu , André Braune , Carlos Mandarim-de-Lacerda , Luís Cristóvão Porto , Alexis Desmoulière

DOI: 10.1078/0344-0338-00447

关键词:

摘要: Wound healing is a complex process that does not always occur harmoniously and may lead to pathological scar development, such as hypertrophic scars keloids. Considering vascularization can play role in the development of these scars, literature controversial, we performed stereological analysis dermal for vessels normal skin, The parameters studied concerned vessels: surface density, length density; myofibroblasts: volume papillary reticular dermis. pattern skin showed no differences. In demis, number was higher keloids than (p < 0.05). Vessels were more dilated those 0.01). dermis, present amount 0.025; p 0.001, respectively). did show any differences between Our results have distinct compared scars. This indicates abnormal be involved

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