作者: Katharina Lutterbeck , Wolfram Eichner , Sven Frie , Cornelius Jungheinrich , Roland Scharpf
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摘要: The invention relates to compounds, comprising a conjugate of hydroxyalkyl starch (HAS) and an active agent, whereby the is either directly covalently bonded or by means linker. further methods for production covalent HAS-active agent conjugate, HAS are reacted in reaction medium, characterised that medium water mixture organic solvent, at least 10 wt. % water.