摘要: The use of local and regional anesthesia in surgical practice is considered to be safe, certainly much safer than the general anesthesia. For example, a 1955 survey used for dental procedures found only two deaths an estimated 90 million cases over span 10 years [1]. Such statistic can lull one into inappropriate sense security. Significant complications other death do occur with anesthetics which cause considerable difficulty patients [2]. incidence adverse reactions blocks hospital setting approximately 0.2% [3] while responses may as high 2.5% [4]. latter figure includes substantial number psychological reactions. It imperative that any physician utilizing understand potential risks prepared manage complications. This chapter covers systemic including allergy, drug interactions, peculiar certain drugs, also reviews precautions should take prevent difficulties.