Prognostic indicators of colon tumors. The Gastrointestinal Tumor Study Group experience.

摘要: This study sought to replicate and expand findings reported by the National Surgical Adjuvant Breast Bowel Project (NSABP) on prognostic factors in resectable colon cancer. Mantel-Haenszel tests Cox model were used analyze significance effect of primary disease symptoms tumor location 572 patients from Gastrointestinal Tumor Study Group (GITSG), with resected Dukes' B2 C (left, right, rectosigmoid/sigmoid) was low importance (P greater than 0.10), did not survival or disease-free 0.10). Obstruction an important indicator prognosis, independent stage = 0.03). perforation is associated poor prognosis 0.001). Rectal bleeding had a positive impact 0.08). Thus, obstruction, perforation, rectal (but location) are found be