A cost-effective protocol for screening patients for methicillin-resistant Staphylococcus aureus.

作者: E. M. Dickson , M. M. Davidson , A. J. Hay , D. O. Ho-Yen

DOI: 10.1080/09674845.2011.11730339

关键词:

摘要: The incidence of hospital-acquired infection with methicillin-resistant Staphylococcus aureus (MRSA) is rising worldwide. Rapid identification MRSA carriers an important step in reducing the risk transmission to other patients. Molecular methods are increasingly popular but technically demanding and expensive. This study assesses modification one commercially available latex agglutination tests (Mastalex-MRSA) for penicillin-binding protein 2’ on known strains as well organisms identified from chromogenic agar plates. A total 3050 patients unknown status were processed through routine laboratory during investigation period 73 these presumptive positive following overnight incubation. Of 70 who could be evaluated, 32 (43.8%) specimens would suitable use kit directly incubation agar, 38 (52.1%) four hours’ ...

参考文章(27)
M Matsuhashi, M D Song, F Ishino, M Wachi, M Doi, M Inoue, K Ubukata, N Yamashita, M Konno, Molecular cloning of the gene of a penicillin-binding protein supposed to cause high resistance to beta-lactam antibiotics in Staphylococcus aureus. Journal of Bacteriology. ,vol. 167, pp. 975- 980 ,(1986) , 10.1128/JB.167.3.975-980.1986
M.J. Struelens, P.M. Hawkey, G.L. French, W. Witte, E. Tacconelli, Laboratory tools and strategies for methicillin-resistant Staphylococcus aureus screening, surveillance and typing: state of the art and unmet needs. Clinical Microbiology and Infection. ,vol. 15, pp. 112- 119 ,(2009) , 10.1111/J.1469-0691.2009.02698.X
L. Rajan, E. Smyth, H. Humphreys, Screening for MRSA in ICU patients. How does PCR compare with culture Journal of Infection. ,vol. 55, pp. 353- 357 ,(2007) , 10.1016/J.JINF.2007.06.005
L. Renwick, A. Hardie, E. K. Girvan, M. Smith, G. Leadbetter, E. Claas, D. Morrison, A. P. Gibb, J. Dave, K. E. Templeton, Detection of meticillin-resistant Staphylococcus aureus and Panton-Valentine leukocidin directly from clinical samples and the development of a multiplex assay using real-time polymerase chain reaction European Journal of Clinical Microbiology & Infectious Diseases. ,vol. 27, pp. 791- 796 ,(2008) , 10.1007/S10096-008-0503-9
Marten Schulz, Claudia Nonnenmacher, Reinier Mutters, Cost-effectiveness of rapid MRSA screening in surgical patients. European Journal of Clinical Microbiology & Infectious Diseases. ,vol. 28, pp. 1291- 1296 ,(2009) , 10.1007/S10096-009-0778-5
R. Cunningham, P. Jenks, J. Northwood, M. Wallis, S. Ferguson, S. Hunt, Effect on MRSA transmission of rapid PCR testing of patients admitted to critical care. Journal of Hospital Infection. ,vol. 65, pp. 24- 28 ,(2007) , 10.1016/J.JHIN.2006.09.019
Laura Gavalda, Cristina Masuet, Juan Beltran, Maria Garcia, Delia Garcia, Josep M Sirvent, Josep M Ramon, None, Comparative cost of selective screening to prevent transmission of methicillin-resistant Staphylococcus aureus (MRSA), compared with the attributable costs of MRSA infection. Infection Control and Hospital Epidemiology. ,vol. 27, pp. 1264- 1266 ,(2006) , 10.1086/507968