The influence of epinephrine upon antigen and antibody action

摘要: I N ORDER to avoid possible untoward reaction from the administration of certain antigenie agents or immune antibody mixtures, use epinephrine either prior coincident with injection has been advocated and is frequently employed apparent success. Thus, for example, in method so-called desensitization horse serum, it suggested1 that be given small doses along each fraction serum. There little question this procedure value prevention serious serum reaction. Likewise, such substances as diphtheria toxoid scarlet fever streptococcus toxin, our practice well other physicians administer 0.1 0.2 cc. every dose order prevent minimize possibility unusual local general In immunizing medical students older children against fever, we have found often prevented subsequent constitutional reactions minimized severity which are more frequent these individuals than younger children. The arisen at times whether inclusion antigen would act any way inhibit its immunologic action. This seemed very unlikely, least a theoretical standpoint, also when one considers pharmacologic action drug. Review available literature failed supply satisfactory answer question. It worth while, therefore, attempt settle definitely by means following experiments :‘f