Portal vein thrombosis and liver transplantation: evolution during 10 years of experience at the University of Bologna.

作者: Matteo Ravaioli , Matteo Zanello , Gian Luca Grazi , Giorgio Ercolani , Matteo Cescon

DOI: 10.1097/SLA.0B013E318206818B

关键词:

摘要: Objective: To evaluate the evolution of liver transplantation (LT) in cases with partial and total portal vein thrombosis (PVT). Background: Portal particular PVT are still surgically demanding conditions, which can exclude patients from LT or increase postoperative complications after LT. Methods: We reviewed our 10-year experience (first era 1998-2002 second 2003-2008), comparing outcome to a group without PVT. Results: Among 889 LTs, we intraoperatively diagnosed 91 PVTs (10.2%): 51 (56%) 40 (44%). The rate complete increased first (2.2% vs. 6.7%, P < 0.005). Partial were mainly treated thrombectomy while managed 26 (63%), jumping graft 6 (15%), portocaval hemitransposition anastomosis varix 3 (7%). no-PVT, mortality was comparable (6.6% 5.8%), as 1- 5-year patient survival rates (85% 68% 86% 73% non-PVT). similar between PVT, but this last group, differed significantly 1 st 2nd (57% 89% at year, 0.05). Conclusions: Liver offers good also selected where surgical innovation has improved results.

参考文章(31)
E. MorenoGonzález, I. Ía Garc García, R. GÖMez Sanz, I. González-Pinto, C. Loinaz Segurola, C. Énez Jim Romero, Liver transplantation in patients with thrombosis of the portal, splenic or superior mesenteric vein British Journal of Surgery. ,vol. 80, pp. 81- 85 ,(2005) , 10.1002/BJS.1800800127
Ernesto P. Molmenti, Thomas W. Roodhouse, Hebe Molmenti, Kshama Jaiswal, Ghap Jung, Shigeru Marubashi, Edmund Q. Sanchez, Brian Gogel, Marlon F. Levy, Robert M. Goldstein, Carlos G. Fasola, Eric E. Elliott, Nevenka Bursac, David Mulligan, Thomas A. Gonwa, Goran B. Klintmalm, Thrombendvenectomy for Organized Portal Vein Thrombosis at the Time of Liver Transplantation Annals of Surgery. ,vol. 235, pp. 292- 296 ,(2002) , 10.1097/00000658-200202000-00019
Matteo Ravaioli, Gian Luca Grazi, Matteo Cescon, Alessandro Cucchetti, Giorgio Ercolani, Michelangelo Fiorentino, Ilaria Panzini, Marco Vivarelli, Giovanni Ramacciato, Massimo Del Gaudio, Gaetano Vetrone, Matteo Zanello, Alessandro Dazzi, Chiara Zanfi, Paolo Di Gioia, Valentina Bertuzzo, Augusto Lauro, Cristina Morelli, Antonio Daniele Pinna, Liver transplantations with donors aged 60 years and above: the low liver damage strategy Transplant International. ,vol. 22, pp. 423- 433 ,(2009) , 10.1111/J.1432-2277.2008.00812.X
D. Cherqui, C. Duvoux, A. Rahmouni, N. Rotman, D. Dhumeaux, M. Julien, P. L. Fagniez, Orthotopic liver transplantation in the presence of partial or total portal vein thrombosis: problems in diagnosis and management. World Journal of Surgery. ,vol. 17, pp. 669- 674 ,(1993) , 10.1007/BF01659140
Neville V. Jamieson, Changing perspectives in portal vein thrombosis and liver transplantation. Transplantation. ,vol. 69, pp. 1772- 1774 ,(2000) , 10.1097/00007890-200005150-00006
J. Figueras, J. Torras, A. Rafecas, J. Fabregat, E. Ramos, G. Moreno, C. Lama, D. Pares, E. Jaurrieta, Extra-anatomic venous graft for portal vein thrombosis in liver transplantation Transplant International. ,vol. 10, pp. 407- 408 ,(1997) , 10.1111/J.1432-2277.1997.TB00940.X
Mehmet Ali Yerdel, Bridget Gunson, Darius Mirza, Kaan Karayal??in, Simon Olliff, John Buckels, David Mayer, Paul McMaster, Jacques Pirenne, Portal vein thrombosis in adults undergoing liver transplantation: risk factors, screening, management, and outcome. Transplantation. ,vol. 69, pp. 1873- 1881 ,(2000) , 10.1097/00007890-200005150-00023
ANDREAS TZAKIS, SATORU TODO, ANDREI STIEBER, THOMAS E. STARZL, Venous jump grafts for liver transplantation in patients with portal vein thrombosis. Transplantation. ,vol. 48, pp. 530- 531 ,(1989) , 10.1097/00007890-198909000-00040
Matteo Cescon, Gian Luca Grazi, Giovanni Varotti, Matteo Ravaioli, Giorgio Ercolani, Andrea Gardini, Antonino Cavallari, Venous outflow reconstructions with the piggyback technique in liver transplantation: a single-center experience of 431 cases. Transplant International. ,vol. 18, pp. 318- 325 ,(2005) , 10.1111/J.1432-2277.2004.00057.X
Jan P. Lerut, Pierre Goffette, Pierre Francois Laterre, Matteo Donataccio, Bernard Van Beers, Jean Bernard Otte, Thierry Puttemans, Véronique Van Leeuw, Jean De Ville De Goyet, Pascal Bourlier, Davide Mazza, Adult liver transplantation and abnormalities of splanchnic veins: experience in 53 patients Transplant International. ,vol. 10, pp. 125- 132 ,(1997) , 10.1007/S001470050025