Failure in presumption of residual disease by quantification of FDG uptake in esophageal squamous cell carcinoma immediately after radiotherapy.
作者： Yoshiharu Tamakawa , Toya Obara , Kenichiroh Ikeda , Kaoru Ishida , Ryuji Nakamura
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摘要: To assess whether differentiation is possible between residual disease and complete response, 18F-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography was performed in 17 cases of primary squamous cell carcinoma the thoracic esophagus before (five control cases) or immediately after full-dose irradiation (12 treated cases). The FDG counts esophageal tumors were corrected by dose injected isotope weight patient, to produce a standardized uptake value (SUV). Endoscopy for post-treatment evaluation showed almost clearance tumor seven (good-responders) apparent other five (poor-responders). There significant difference average median SUV controls (8.1 +/- 1.6 vs. 3.3 1.1), poor-responders good-responders (4.1 0.8 2.7 0.9). Three locoregional recurrence four, six, 18 months. Among good-responders, local not inevitably higher than that others. rate irradiated cancer approximately represents response radiotherapy, but it seemed impossible differentiate from response.
参考文章(12)
G Ganem, B Dubray, Y Raoul, P Colin, E Bardet, J Y Douillard, M J Goudier, C Hennequin, S Walter, P Michel-Langlet, P Martin, D Maron, F Morvan, P Andolenko, J M Extra, Concomitant chemoradiotherapy followed, where feasible, by surgery for cancer of the esophagus. Journal of Clinical Oncology. ,vol. 15, pp. 701- 711 ,(1997) , 10.1200/JCO.1997.15.2.701
E S Lambright, S M Albelda, H Zhuang, M Pourdehnad, M D Rossman, A Alavi, A J Yamamoto, P Li, M Lanuti, P D Mozley, Dual Time Point 18F-FDG PET Imaging for Differentiating Malignant from Inflammatory Processes The Journal of Nuclear Medicine. ,vol. 42, pp. 1412- 1417 ,(2001)
Anne-Marie Mandard, Frédéric Dalibard, Jean-Claude Mandard, Jacques Marnay, Michel Henry-Amar, Jean-François Petiot, Alain Roussel, Jacques-Henry Jacob, Philippe Segol, Guy Samama, Jean-Marie Ollivier, Sylvie Bonvalot, Marc Gignoux, Pathologic Assessment of Tumor Regression After Preoperative Chemoradiotherapy of Esophageal Carcinoma. Clinicopathologic Correlations Cancer. ,vol. 73, pp. 2680- 2686 ,(1994) , 10.1002/1097-0142(19940601)73:11<2680::AID-CNCR2820731105>3.0.CO;2-C
Ichiro Akakura, Yoshizo Nakamura, Temo Kakegawa, Ryuichi Nakayama, Hiroshi Watanabe, Hisao Yamashita, Surgery of carcinoma of the esophagus with preoperative radiation. Chest. ,vol. 57, pp. 47- 57 ,(1970) , 10.1378/CHEST.57.1.47
Stephen B. Vogel, William M. Mendenhall, Michael D. Sombeck, Robert Marsh, Edward R. Woodward, Downstaging of esophageal cancer after preoperative radiation and chemotherapy. Annals of Surgery. ,vol. 221, pp. 685- 695 ,(1995) , 10.1097/00000658-199506000-00008
Christophe Hennequin, Brice Gayet, Alain Sauvanet, Anne Blazy, Thierry Perniceni, Yves Panis, Frédéric Mal, Emile Sarfati, Patrice Valleur, Jacques Belghiti, François Fekete, Claude Maylin, Impact on survival of surgery after concomitant chemoradiotherapy for locally advanced cancers of the esophagus International Journal of Radiation Oncology Biology Physics. ,vol. 49, pp. 657- 664 ,(2001) , 10.1016/S0360-3016(00)01399-7
Björn L.D.M. Brücher, Wolfgang Weber, Markus Bauer, Ullrich Fink, Norbert Avril, Hubert J. Stein, Martin Werner, Frank Zimmerman, J. Rüdiger Siewert, Markus Schwaiger, Neoadjuvant Therapy of Esophageal Squamous Cell Carcinoma: Response Evaluation by Positron Emission Tomography Annals of Surgery. ,vol. 233, pp. 300- 309 ,(2001) , 10.1097/00000658-200103000-00002
Ludwig G. Strauss, Fluorine-18 deoxyglucose and false-positive results: a major problem in the diagnostics of oncological patients. European Journal of Nuclear Medicine and Molecular Imaging. ,vol. 23, pp. 1409- 1415 ,(1996) , 10.1007/BF01367602
KARL F. HÜBNER, EDWARD BUONOCORE, HOWARD R. GOULD, JOE THIE, GARY T. SMITH, SHAWN STEPHENS, JENNIFER DICKEY, Differentiating benign from malignant lung lesions using "quantitative" parameters of FDG PET images. Clinical Nuclear Medicine. ,vol. 21, pp. 941- 949 ,(1996) , 10.1097/00003072-199612000-00005
F L Flanagan, F Dehdashti, B A Siegel, D D Trask, S R Sundaresan, G A Patterson, J D Cooper, Staging of esophageal cancer with 18F-fluorodeoxyglucose positron emission tomography American Journal of Roentgenology. ,vol. 168, pp. 417- 424 ,(1997) , 10.2214/AJR.168.2.9016218