Spinal fractures in ankylosing spondylitis: prevalence, prevention and management

摘要: In patients with ankylosing spondylitis (AS), the risk of vertebral fractures (VFs) is increased. Case finding and in AS a clinical challenge for several reasons. First, back pain hyperkyphosis are mostly attributed to disease-related inflammation structural damage terms erosions syndesmophytes, not an eventual VF. Second, most frequent VFs classical wedging, biconcave or crush as seen postmenopausal women elderly, but once multilevel ankylosis spine manifested, can also occur other parts directions vertebrae (transvertebral, dorsal arch structures through ankylosed extravertebral calcifications ligaments intervertebral discs) cervical spine. Diagnosis these atypical much more difficult. Besides pathology general AS, associated result irreversible neurological com...