摘要: Obsessive-compulsive disorder (OCD) has long been associated with epilepsy The link temporal lobe (usually refractory) (TLE) is particularly prominent Of TLE patients, 10% to 22% of patients may have OCD, often underdiagnosed in the outpatient clinic. Data on links include case reports, series, and controlled studies. Three larger, studies using comprehensive OCD classifications, aggregate, noted obsessive qualities washing, symmetry/exactness, ordering, a greater preoccupation certain aspects religion, compared controls or idiopathic generalized epilepsy. foci be either left- right-sided. Social neurobiological factors are involved TLE. neurobiology implicates pathophysiological structural impairment orbitofrontal-thalamic, fronto-thalamic-pallidal-striatal-anterior cingulate-frontal circuits. Discrete anatomic lesions these pathways, their surgical removal, induce (or conversely) improve patients.
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