摘要: Fungicide resistance is a problem which followed the development of antifungals with specific biochemical modes action. It not surprising that primary mechanism to these new fungicides target site based. The most characterized example fungicide based on modified benzimidazole class such as carbendazim. Several laboratory studies have clearly shown by genetic and analysis tubulin resistance. Resistance mechanisms compounds phenylamides, carboxamides, polyoxins, sterol biosynthesis inhibitors been investigated will be discussed exemplify diversity used fungi circumvent toxicity modern disease control agents.