Thiamin and Thiamin Phosphate Ester Deficiency Assessed by High Performance Liquid Chromatography in Four Clinical Cases of Wernicke Encephalopathy

作者: C. M. E. Tallaksen , H. Bell , T. Bohmer

DOI: 10.1111/J.1530-0277.1993.TB00825.X

关键词:

摘要: The concentrations of thiamin and phosphate esters were determined by high performance liquid chromatography in four patients with clinical Wernicke encephalopathy. Three alcohol abusers, one had prolonged vomiting anorexia. Thiamin monophosphate assessed plasma whole blood (four patients) cerebrospinal fluid (two before during treatment. diphosphate was also the patients. Before treatment, significantly decreased all patients, three. A poor increase mono- paralleled a slow improvement patient, while an compounds observed two rapid recovery. more sensitive marker deficiency than unphosphorylated thiamin.

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