A Model Based Analysis of IPEC Dosing of Paclitaxel in Rats

作者: Pieter Colin , Lieselotte De Smet , Chris Vervaet , Jean-Paul Remon , Wim Ceelen

DOI: 10.1007/S11095-014-1384-5

关键词:

摘要: Purpose A strong pharmacokinetic rational exists for the use of (Hyperthermic) Intraperitoneal Perioperative Chemotherapy in peritoneal carcinomatosis. However, controversy remains regarding optimal treatment strategies. Paclitaxel is believed to be a good compound IPEC because its favourable properties.

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