Treatment of experimental total hyphema with intraocular fibrinolytic agents.

摘要: Traumatic hyphema is always potentially dangerous. Total ("eight-ball hemorrhage") has an especially poor prognosis because it often results in glaucoma, iris atrophy, and hematogenous pigmentation of the cornea. The types treatment advocated for traumatic include bed rest, sedatives, miotics, mydriatics, carbonic anhydrase inhibitors, cold compresses. Some favor repeated paracenteses if intraocular pressure rises. 2 Early paracentesis injection air have been advocated. 3 When there secondary bleeding anterior chamber becomes filled with blood, many operators advocate early surgery irrigation manual removal clot. 1 Enzymatic dissolution also attempted. Results intramuscular trypsin are equivocal. 4,5 Jukofsky 6 first suggested use streptokinase. rabbit blood was injected into eyes streptokinase, clots dissolved, but corneas became opaque. One total a human patient cleared. Adverse reactions to including chemosis iritis,