Cancer, Genes, and Development: The Drosophila Case

摘要: Publisher Summary This chapter describes the different types of benign and malignant neoplasms found in 25 Drosophila mutants discusses these light recent findings. In , a total 5000 genes have been to cause or mutated state. These play crucial roles differentiation specific cell tissues. The wild-type alleles control particular pathways development tissues cells at times. involved include adult optic neuroblasts, imaginal discs, primordial blood larva, male female gonial adult, cells, other not yet identified embryo. Moreover, understand primary events leading neoplastic transformation, insight has be gained into genetics normal development.